To Vaccine, Or Not To Vaccine?
So I have been getting several questions about the recent COVID-19 vaccine— at work and via inbox— soooo I decided to compile them all and answer them here! There is much controversy about the vaccine as well so I just want to clear up the fog in order for you all to make the most informed decision for you and your loved ones. Let's jump into the questions!
Q: Do you trust the vaccine?
A: I do. I believe in the science that experts so carefully studied and executed. Not only are vaccines one of the most effective ways to control infectious disease, but they also can help to prevent them. The COVID-19 vaccine that is out currently uses mRNA-based technology that has been studied for over two decades. The immune response shown by animals and in early human clinical trials prove to be powerful and effective. Other vaccines using this technology include: flu, Zika virus, and rabies.
The vaccine uses a non-infectious element, has shorter manufacturing times, and can be used to target multiple diseases. They can be made in a lab using a DNA template and readily available materials, hence the vaccine being produced so quickly. We already had the blueprint!
Q: Is it safe?
A: Like all vaccines, the COVID-19 vaccine has been carefully and meticulously tested for safety before its authorization for use in the US by the FDA. The data has been reviewed by a safety monitoring board in large clinical trials. These vaccines are not live, or do not use an infectious element, so there is zero risk of causing disease in the person.
Q: How does the vaccine work?
A: mRNA vaccines have strands of genetic material called mRNA that's wrapped in a special coating. This coating protects the mRNA from being broken down by the body's enzymes. This coating also helps the mRNA to enter the cells in the lymph node near the vaccination site (so if you develop a lump near the site, it’s totally normal).
So mRNA basically gives directions to the cell on how to make a piece of the “spike protein” that is unique to SARS-CoV-2. Kind of like the owner of a club showing the bouncer a picture of someone who is not allowed in, so if they somehow get in, the bouncer will know who to throw out. The spike protein is found on the surface of the SARS-CoV-2 which causes COVID. And since only part of the protein is made, it doesn’t do any harm to the patient but is still a foreign substance therefore stimulating the immune system.
After the piece of protein is made, the cells’ enzymes break down the mRNA strand and gets rid of them. The mRNA strand NEVER enters the cell’s nucleus or affects genetic makeup.
Once displayed on the cell surface, the protein or antigen causes the immune system to start making antibodies and activating our T-cells to fight off what it thinks is an infection. The antibodies are specific to the SARS-CoV-2 virus, which means the immune system is now equipped to protect against future infection.
Q: Is this vaccine going to interfere with my DNA?
A: The mRNA from the vaccine never enters the nucleus of the cell and doesn’t affect or interact with your DNA in any way. The cell breaks down and gets rid of the mRNA soon after it is finished with the instructions via enzymes.
Q: What's going to happen to me after I get it?
A: You may experience sore muscles, fatigue, and a mild fever. This means the vaccine is working hard to help teach your body how to fight off the virus; just think about it as class is in session lol. These side effects should only last around two days and do NOT mean that you have COVID-19. Please don’t go around saying the vaccine gave you COVID lol. Contact your doctor or health clinic for questions.
Q: Should I still get the vaccine even if I’ve had COVID-19?
A: Short answer, yes. Due to the risks associated with the disease and the fact that reinfection is possible, it is recommended to get the vaccine. You develop a natural immunity from having and recovering from COVID but this varies from person to person. Since this disease is still new, we don’t know how long this immunity lasts so it is recommended to still get the vaccine until we know more information.
Q: Can I get my flu shot along with the COVID vaccine?
A: Since we don't have much information yet on how this vaccine interacts with others, it is best to wait 14 days before or after receiving another vaccine.
Q: I don’t like needles. Do I HAVE to get both shots?
A: I'm sorry, sweetie but yes. Different types of vaccines will soon be available and most will be given in two parts. The first shot gets your body prepared. The second shot—depending on which manufacturer you receive—is to make sure you have full protection. The second Pfizer shot will be given at around 21 days and for Moderna, 28 days. NOTE: IT IS IMPORTANT TO STAY WITH THE SAME MANUFACTURER AS THE TWO ARE NOT INTERCHANGEABLE!
Q: Do I still have to wear a mask and social distance if I’ve gotten my two doses?
A: Unfortunately for now, yes. The experts need more information about the protection that the vaccine provides in real-world conditions. Scientists also don’t know yet if the vaccine will help prevent the transmission even if you personally don’t get sick yourself. Also, the vaccine is not available to all. So in order to protect your communities for now, continue to wear your mask and socially distance!
Q: Can my husband and two kids get the vaccine with me?
A: Well, it all depends on how old your kids are. The vaccine has only been authorized in people ages 16 and older, so far.
Q: Can I do anything to help with the side effects?
A: To help minimize the side effects, you can take 40 mg of famotidine (generic Pepcid) and a Zyrtec 30 minutes prior to getting the injection. This helps to lessen the histamine response. But try to reserve ibuprofen for after due to the possibility of interfering with the immune response.
Hopefully after reading this, I've either answered your question, relieved some anxiety, or both! Those are the most common questions that I've encountered but if you still have some questions, feel free to contact me! Thank you for reading and as always,
Much love!
References:
CDC website and coworkers!